Courses
MBGE 491
Available to students with a GPA equal to or greater than 3.00 and with consent of the instructor.
MBGE 502
The ability to communicate results and interpretation effectively is key to success in the biological sciences. This course will improve the skills of students in conveying their findings in lectures, research posters, and research publications.
MBGE 505
The key areas of RNA biology, structure and function; splicing, polyadenylation, transport, translation and decay of mRNAs; the regulatory mechanisms governed by noncoding RNAs such as siRNAs, miRNAs and long noncoding RNAs.
MBGE 510
Cells have elaborate mechanisms for controlling cell proliferation and differentiation. In this course, we will explore in molecular detail the intricate signaling pathways that are important for cell behavior, with a major focus on those pathways that are conserved widely among many species.
MBGE 518
The journey of a fertilized egg to turn into a fully developed adult, the molecular mechanisms that regulate the animal development in two vertebrate (mouse, fish) and two invertebrate (fly, worm) models; body plan formation, organogenesis, morphogenesis, regeneration and ageing.
MBGE 501
The advanced methodology used for modern biological science research. Topics include the interpretation of data gained from both hypothesis-driven and high-throughput experiments from research articles focusing on DNA repair, DNA replication, transcription, cell cycle, organelle biogenesis, proteomics and genetics.
MBGE 504
Molecular details of the innate and adaptive immune systems. Subject areas will include immune recognition, immunosuppression, communication between different immune system cell types, and autoimmunity.
MBGE 508
Proteomics and function, fundamentals of mass spectrometry (MS), tandem MS, chemical and posttranslational modifications, protein identification, data mining, protein complexes, protein folding, MS genotyping, high throughput; recently developed proteomics methods and their applications; focus on the recent scientific literature in this field including quantitative comparison of healthy and disease proteomes, the comprehensive analysis of protein-protein interactions in different cell types, and new approaches to analyze cellular signaling pathways and the subcellular-organelle and cell surface proteomes.
MBGE 515
Broad cross section of methodological approaches including cloning, genomic strategies, single molecule and single cell-based studies, in situ localization, high troughput approaches such as RNAi, gene expression analysis, genetic approaches with model systems as well as techniques for protein analysis.
MBGE 523
The key concepts and techniques related to the prokaryotic and eukaryotic cytoskeleton including the molecular mechanism of the core building blocks, nucleators, molecular motors and regulators of actin and microtubule cytoskeleton and intermediate filaments, roles of the cytoskeleton in the physiology of individual cells, tissues and organisms and their implications in human disease, emerging techniques to study the cytoskeletal components such as advanced microscopy.
MBGE 495
Students will carry out independent research under the supervision of a faculty in the field of molecular biology and genetics.
MBGE 503
Energy generation in the cell, energy storage mechanisms and use; the processes of oxidative phosphorylation, glycolysis, and photosynthesis; energy acquisition mechanism by chemotrophic organisms.
MBGE 507
The cell and molecular biology of pathogenic organisms, such as malaria, trypanosomes, toxoplasma, and parasitic yeast. Organism life cycles, host invasion strategies, methods of immune system evasion, and the evolution of parasites.
MBGE 512
Fundamental aspects of the molecular and cellular biology of tumor formation and cancer cells. Topics include cell cycle, oncogenes, tumor suppressor genes, the tumor's interaction with other cells and tissues, approaches to treating cancer, and novel experimental approaches for the discovery of mutations that contribute to tumorigenesis.
MBGE 520
Function of different neuronal cell types and the larger organization of the mammalian nervous system: The topics include the molecular details of synaptic connectivity and its relationship to learning and memory and the causes of neurodegenerative disease.
